This test is prescribed to monitor results of treatment for liver or bone disorder.
Alkaline phosphatase (ALP) is an enzyme. Different kinds of this protein are present on different parts of the body. The different forms of ALP are called isoenzymes. ALP is found especially in bone cells and liver cells. Smaller amounts of ALP are present in the placenta and in the bowels.
Its concentration is measured by means of analysis of a blood sample drawn from the vein in the arm.
Purpose of the test
The measurement of the ALP protein concentration in blood is import to determine whether a person has certain types of liver disease.
Very high ALP levels can mean that bile ducts are blocked. ALP is also high in persons who have cancer that has spread to the liver or the bones. If the person recovers from the illness, ALP levels decrease.
ALP is generally proposed as part of a set of test in order to determine liver or bone disorder.
Reference range values
Person over 18 years old : 37 – 116 U/L
Below 18 years old (U/L) :
1D-30D 75 - 316
31D-365D 82 - 383
1Y-3Y 104 - 345
4Y-6Y 93 - 309
7Y-9Y 86 - 315
10Y-12Y 42 - 362
13Y-15Y 74 - 390
16Y-18Y 52 – 171
1D-30D 48 - 406
31D-365D 124 - 341
1Y-3Y 108 - 317
4Y-6Y 96 - 297
7Y-9Y 69 - 325
10Y-12Y 51 - 332
13Y-15Y 50 - 162
16Y-18Y 47 – 119
High ALP levels usually can mean:
· Bone or liver damage.
o If bilirubin test, AST test, or ALT test are also high it can mean liver damage.
o If calcium and phosphate measurements are abnormal it can mean bone damage.
· Use of psychiatric drugs.
ALP levels are higher during pregnancy and childhood.