Plasminogen
Category:
Plasminogen
Description
This test measures plasminogen enzyme in blood.
Its concentration is measured by means of analysis of a blood sample drawn from the vein in the arm.
Purpose of the test
This test is used to evaluate thromboembolic disorders, including ligneous conjuctivitis (a type of mucous membrane abnormality).
This test is normally prescribed when searching for the following diseases:
• Disorder involving the fibrinolytic system
• Ligneous conjunctivitis
Reference range values
Adults:
o Functional assay: 80%-130%
o Antigenic assay: 84-140 mg/L
Neonates: 60% of adult value
Abnormal findings
Apart from ligneous conjunctivitis and problems involving fibrinolytic system, there are another circumstances on which abnormal levels can result from this test:
High levels of plasminogen can be seen in:
o Pregnancy (peak of 165% of normal in third trimester)
o Increased triglyceride and/or cholesterol levels
Low levels of plasminogen can be seen in:
o Liver disease
o Consumptive coagulopathies
o Fibrinolytic therapy
o DIC
o Advanced age