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Albumin, Serum

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Description

Albumin is an important protein present in the blood plasma. It prevents fluid from leaking out of blood vessels. Also it transports substances such as hormones, vitamins, drugs, and ions like calcium. Albumin is produced in the liver, and its concentration is sensitive to liver damage. Its concentration is measured by means of analysis of a blood sample drawn from vein in the arm.


Purpose of the test

This test helps detecting a liver disease such as kidney disease. It is also applied in order to evaluate nutritional status. It is prescribed when you have a rapid weight change, or prior to a planned surgery.

Albumin concentration drops with damaged liver or kidney disease also when a person is malnourished or experiences inflammation in the body, or shock. Albumin increases when a person is dehydrated.
Albumin testing is used in a variety of situations to diagnose disease and to monitor changes in health status with treatment.

Doctor orders a blood albumin test after symptoms of liver disorder or nephrotic syndrome. Also in order to check a person's nutritional status, for example, after an important lose of weight.


Reference range values (North America)

3.7-4.7 g/L

Abnormal findings

Low albumin levels usually can mean:

· Liver disease.

· Kidney diseases. Albumin in the urine must also then be checked in order to determine if kidneys cannot prevent albumin from leaking into the urine and being lost.

· Inflammation, shock, or malnutrition.

· Diseases related to bad absorption of protein: Crohn's disease or sprue

· Lose of protein from the intestines.

High albumin levels usually can mean:

· Dehydration.

· Presence of certain drugs: anabolic steroids, androgens, growth hormones, and insulin.

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