Test Includes: Methadone screen, urine.
Additional Information: Methadone is a synthetic diphenylheptane derivative. Methadone is approximately equal in analgesic properties to morphine but produces less euphoria than morphine. Methadone is highly addictive, but the withdrawal symptoms are less intense. This drug is used in the management of severe pain and in narcotic detoxification maintenance programs. Onset of action is 30 to 60 minutes after oral dose and 10 to 20 minutes following parenteral administration. The half-life is 15 to 55 hours. Adverse effects include marked sedation after repeated administration, CNS and respiratory depression, nausea and vomiting, bradycardia, hypotension, increased intracranial pressure, miosis, antidiuretic hormone release, and physical and psychological dependence. This drug is included in most drug-of-abuse profiles.