Rh typing is used in determine Rho(D) typing for transfusion candidates. Rho(D) typing of expectant mothers may indicate potential for Rh hemolytic disease. This typing is also used to determine Rh immune globulin candidacy for prenatal and postpartum patients.
Limitations
The presence of potent cold autoagglutinins, positive direct antiglobulin test, and, in some cases, bacteremia may interfere with test interpretation. Variable testing results may be observed with partial antigens which are rare variants of the Rho(D) antigen.